GBA1 mutations impair ciliary Hedgehog signaling in Parkinson's disease, reducing neuroprotective factors and highlighting a ...

A rare cell in the lining of lungs is fundamental to the organ-wide response necessary to repair damage from toxins like those in wildfire smoke or respiratory viruses, Stanford Medicine researchers ...

The Sonic hedgehog, a critical embryonic signaling pathway conserved from fruit flies to humans, which is involved in cell differentiation, proliferation, and anterior-posterior patterning during ...

Vital Pathway The Hedgehog pathway is highly conserved in evolution. The cell-signaling pathway is active in embryogenesis, tissue proliferation, and organ development.

This disruption in sonic hedgehog signaling means that needed neuroprotective factors are not produced. "Many kinds of processes necessary for cells to survive are regulated through cilia sending ...

Elusive cytonemes guide neural development, provide signaling 'express route' Date: January 2, 2024 Source: St. Jude Children's Research Hospital Summary: Discover the first images of cytonemes ...