Scientists reveal how G protein-coupled receptors, major therapeutic drug targets, decode critical properties of their ligands. Through an international collaboration, scientists at St. Jude ...
About one-third of all drugs approved by the Food and Drug Administration target the largest family of cell membrane receptors called G protein-coupled receptors (GPCRs). GPCRs are indispensable for ...
Scientists have discovered how chemokines and G protein-coupled receptors selectively bind each other to control how cells move. Scientists from St. Jude Children's Research Hospital and the Medical ...
Whenever I interview the founders of a new biotech company, I typically inquire about the origin of the company’s name. There is an astonishingly wide range of responses to this question. A few days ...
Chemerin is a key adipokine that regulates lipid metabolism and insulin sensitivity, and thus is involved in many metabolic ...
Activating the GPR133 receptor with a small molecule can rebuild bone from within, offering a new direction for osteoporosis ...
Through an international collaboration, scientists at St. Jude Children’s Research Hospital leveraged data science, pharmacology and structural information to conduct an atomic-level investigation ...
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