Little is currently known about the molecular determinants of energy barriers along enzyme catalytic pathways. Kern and co-workers have studied this question in adenylate kinase (Adk) and now reveal ...

Researchers have identified a molecule sent by fat cells to the fly brain that senses when they have had enough food and inhibits feeding. Researchers have identified a molecule sent by fat cells to ...

A peptide bridge is designed to construct a fusion enzyme with electrostatic cofactor channeling, reducing NADPH input by two orders of magnitude or decreasing reaction time threefold with the same ...

Cells use flavin monooxygenases to break down foreign molecules by adding oxygen atoms to them. Biochemists have long assumed that the enzymes use a particular cofactor adduct to add the oxygen. A new ...

Hydrogenases catalyze the reversible splitting and production of hydrogen gas (H2), using complex catalytic cofactors comprising Earth-abundant nickel and/or iron ions. These enzymes, especially the ...

This is a preview. Log in through your library . Abstract The flavin cofactor in photoenzyme phototyase and photoreceptor cryptochrome may exist in an oxidized state and should be converted into ...

Researchers at the Indian Institute of Science (IISc) have developed a highly efficient cell-free enzyme system that converts fatty acids into 1-alkenes—versatile hydrocarbons that can serve as ...

Enzymes perform very specific functions and require only little energy -- which is why the biocatalysts are also of interest to the chemical industry. Biologists have now provided a summary on what is ...