Figure 1: p53-family-based cell-fate decisions. Figure 2: p53 family functions in myogenic differentiation and in rhabdomyosarcoma. Even in the modern era of cancer genomics, the classic ...

ATP-dependent chromatin-remodelling enzymes use the energy of ATP hydrolysis to alter histone–DNA contacts and to facilitate changes in chromatin structure. These are important steps in the regulation ...

Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace ...

Da-Sol Kuen, Miso Park, Heeju Ryu, Garam Choi, Young-Hye Moon, Jae-Ouk Kim, Keon Wook Kang, Sang Geon Kim, Yeonseok Chung Proceedings of the National Academy of Sciences of the United States of ...

The human genome contains over 4.5 million sequences of DNA called “transposable elements”, these virus-like entities that “jump” around and help regulate gene expression. They do this by binding ...

Revise differentiation of algebraic and trigonometric expressions, which can be used for calculating rates of change, stationary points and their nature, or the gradient and equation of a tangent to a ...