This protocol describes the design of a cyclic herpes simplex 1 virus-thymidine kinase reporter and its use in PET imaging of chemotherapy-induced apoptosis in cancer cells in vitro and in vivo.

Cyclic olefins such as norbornenes, cyclooctenes, cyclobutadienes and many others can also be substituted with a large range of functional groups, giving rise to highly functional polymers with ...

A mutant DJ-1 gene causes recessive Parkinson's disease, but the molecular mechanism of this process has not been well ...

E. Rips, Z. Sela, Cyclic Splittings of Finitely Presented Groups and the Canonical JSJ Decomposition, Annals of Mathematics, Vol. 146, No. 1 (Jul., 1997), pp. 53-109 ...

For each natural number n we determine the average order α (n) of the elements in a cyclic group of order n. We show that more than half of the contribution to α (n) comes from the φ (n) primitive ...