Rabies is notoriously difficult to treat once symptoms begin, and that challenge starts at the molecular level. Unlike many ...

Nipah virus is a zoonotic virus harbored by fruit bats. It can be transmitted to pigs and humans, infect people through contaminated food, and can travel directly from person to person via droplets.

"The E1E2 complex is very flimsy - it's like a bag of wet spaghetti, always changing its shape - and that's why it's been extremely challenging to image at high resolution," says co-first author ...

Cryo-EM reconstruction showing the surface of the Zika virus is shown. A team led by Purdue University researchers is the first to determine the structure of the Zika virus, which provided insights ...

Scientists at Harvard Medical School and Boston University Chobanian & Avedisian School of Medicine have mapped a critical component of the Nipah virus, a highly lethal bat-borne pathogen that has ...

Based on the resolved structure of the NiV polymerase L-P complex, this study identified two conserved zinc-binding sites within the PRNTase domain and characterized the L-P interaction interface.

In a recent landmark study, scientists have unveiled how HIV-1 penetrates the cell's nuclear barrier—a discovery that could reshape antiviral strategies. The research, led by Professor Peijun Zhang, ...

They determined the holoenzyme structure in complex with DNA using cryo-electron microscopy at the global resolution of ~2.8 Å.

Structural basis for Ebola virus nucleocapsid assembly and function regulated by VP24. Nature Communications, 2025; 16 (1) DOI: 10.1038/s41467-025-57236-4 ...

Their findings published in Cell on Jan. 31, 2024. Left: the three-dimensional structure of a PNMA2 complex, which can trigger a dangerous immune reaction when released by tumor cells. Image credit: ...