The eukaryotic structural maintenance of chromosomes (SMC) complexes cohesin, condensin and the SMC5/6 complex organize chromosome structure through their association with DNA and influence a large ...

A hallmark of cancerous cells is an abnormal number of chromosomes or chromosome arms, known as aneuploidy. While aneuploidy ...

New light has been shed on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a process ...

In a report published in the Proceedings of the National Academy of Sciences, researchers working at Florida State University (FSU), Baylor College of Medicine and the Broad Institute of Harvard and ...

The role of sex in human disease is a growing area of research. Although estrogen (in females) and androgens (in males) are often seen as possible causes for such differences, sex chromosomes, ...

Tatiana Schlossberg, the youngest granddaughter of President John F. Kennedy, recently revealed she was diagnosed with ...

Human artificial chromosomes (HACs) could be useful tools for both understanding how mammalian chromosomes function and creating synthetic biological systems, but for the last 20 years, they have been ...

Research showed that a regulatory protein of chromosome structure (cohesin) is essential for proper maintenance of gene expression in the developing brain. Reduced cohesin impaired development of ...

Scientists have uncovered an unexpected function for a crucial protein involved in cell division. Reported in two consecutive ...

The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

AMES, Iowa – A new study led by an Iowa State University scientist sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, ...