Chromosomal aberrations, encompassing both structural and numerical chromosome abnormalities, are fundamental indicators of genomic instability with far‐reaching implications for cancer risk. These ...

Chromosomal instability plays a crucial role in the progression of cancer: it shapes the properties of tumor cells and drives the development of therapy resistance. Scientists used state-of-the-art ...

Cancer’s most catastrophic DNA damage has long looked like a crime scene without a culprit, with chromosomes shattered and ...

Quality of life and lifestyle changes during and after therapy in women with endometrial cancer: A global study of 1,066 patients (NOGGO, ENGOT, GCIG, ENGAGe-IMPROVE ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which ...

University of California San Diego researchers have discovered the enzyme responsible for chromothripsis, a process in which a single chromosome is shattered into pieces and rearranged in a scrambled ...

They discovered that cells with 'driver' mutations in cancer genes occupy almost 10 per cent of the gastric lining by age 60. Plus an unusual discovery that some individuals, but not all, had ...

Osteosarcoma is a type of aggressive bone cancer that most commonly affects children and young adults between the ages of 10 and 20, during times of rapid bone growth. Although rare, it has a ...

Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells by co-opting a process used to maintain cellular identity through ...

For the first time, scientists have systematically analyzed somatic mutations in stomach lining tissue to unpick mutational ...