A study conducted by the Development and Growth Control Laboratory at IRB Barcelona sheds light on the contribution of DNA damage to the invasiveness of cancer cells. The discovery challenges the ...
Chromosomal instability is a phenomenon characterized by rapid changes in the number and structure of chromosomes during cell division. It is very common in solid tumors and it is linked to the ...
Quality of life and lifestyle changes during and after therapy in women with endometrial cancer: A global study of 1,066 patients (NOGGO, ENGOT, GCIG, ENGAGe-IMPROVE ...
A new tool, ContactTracing, enabled researchers to show that chronic activation of the STING pathway, induced by chromosomal instability (CIN), promotes downstream changes in cellular signaling. This ...
Chromosomal instability (CIN) is a defining characteristic of most human cancers. Mutation of CIN genes increases the probability that whole chromosomes or large fractions of chromosomes are gained or ...
New research finds an unexpected link between chromosomal instability and epigenetic alternations, both of which are hallmarks of cancer -- especially advanced, drug-resistant cancers. A graduate ...
As it transitions from a discovery- to a clinical-stage biotech, Volastra Therapeutics is bringing longtime adviser Samuel Bakhoum, M.D., Ph.D., on board as its chief scientific officer. Bakhoum is a ...
Triple negative breast cancer (TNBC) is one of the most aggressive and hardest forms of breast cancer to treat, but a new study led by Weill Cornell Medicine suggests a surprising way to stop it from ...