Because membrane receptors interact with both extracellular signals and molecules within the cell, they permit signaling molecules to affect cell function without actually entering the cell.

ERBB receptors are regulated by their own intrinsic properties as well as by external associated proteins. What is regulation, where does it occur on the receptor, and how do scientists study it?

Alterations in thyroid gland function result from the action of stimulating or blocking autoantibodies on cell membrane receptors. Three principal thyroid autoantigens are involved in AITD.

Irritable bowel syndrome, chronic itching, asthma and migraine are in many cases hard-to-treat conditions. They have in ...

Engineered cell therapies rely on synthetic receptors to transduce external ... of how NTEVp and CTEVp might orient ...

Lipids in cell membranes regulate the activity of a cancer-linked protein, cell biologists at RIKEN have discovered. This ...

Cell membrane proteins hide secret gateways that ... how membrane lipids interact with G protein-coupled receptors (GPCRs) in their natural environment. These interactions reveal new ways to ...

However, the mechanisms underlying interorgan transport and exogenous ceramide's regulation of target cells remain unclear ... existence of unidentified membrane receptor-mediated mechanisms ...

New research challenges the view that proteins are the only key to evolution, highlighting the importance of lipids.

When bound to the receptor, toxins can act at the cell membrane by interfering with signal transduction pathways, pore formation or enzymatic activities on membrane compounds. Various enterotoxins ...