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For example, membrane receptors bind and respond to specific molecules outside the cell, such as hormones, neurotransmitters, the extracellular matrix, and attachment molecules on other cells.
Because membrane receptors interact with both extracellular signals and molecules within the cell, they permit signaling molecules to affect cell function without actually entering the cell.
Lipids in cell membranes regulate the activity of a cancer-linked protein, cell biologists at RIKEN have discovered. This ...
Cell membrane proteins hide secret gateways that ... how membrane lipids interact with G protein-coupled receptors (GPCRs) in their natural environment. These interactions reveal new ways to ...
Proteins are life's engines, powering processes like muscle movement, vision, and chemical reactions. Their environments—water, lipid membranes, or other condensed phases—are critical to their ...
Cell membrane proteins hide secret gateways that ... In fact, 34% of FDA-approved drugs are based on these receptors. "Having detailed information about the specific site where these drugs act ...
However, the mechanisms underlying interorgan transport and exogenous ceramide's regulation of target cells remain unclear ... existence of unidentified membrane receptor-mediated mechanisms ...
BLyS is a protein member of the TNF ligand superfamily and binds to three different B-cell membrane receptors, namely the transmembrane activator and calcium-modulating cyclophilin ligand ...
When bound to the receptor, toxins can act at the cell membrane by interfering with signal transduction pathways, pore formation or enzymatic activities on membrane compounds. Various enterotoxins ...
A team of Chinese researchers led by Prof. WANG Likun from the Institute of Biophysics of the Chinese Academy of Sciences has provided new insights into metabolic disease mechanisms and potential ...