By transferring mouse aged hematopoietic stem cells (aged HSCs, *1) to the environment of young mice (bone marrow niche, *2), it was demonstrated that the pattern of stem cell gene expression was ...

Bone marrow (BM) stem cell reserves and function and stromal cell hematopoiesis supporting capacity were evaluated in 15 patients with multiple sclerosis (MS) and 61 normal controls using flow ...

Sepsis, an inflammatory syndrome that occurs when the body has an extreme response to an infection, is responsible for about 20% of deaths worldwide. A new study by researchers at Baylor College of ...

More than 50,000 stem cell transplants are performed each year worldwide. Scientists may have solved a major issue of expanding adult hematopoietic stem cells outside the human body for clinical ...

In human adults, hematopoietic stem and progenitor cells (HSPCs) reside in the bone marrow (BM), but our understanding of how different types of blood cells are formed and the biology of bone ...

For the past decade, King’s lab has worked to characterize the impact of infection and inflammation on bone marrow hematopoietic stem cell function, and this research reportedly is the first to ...

Preclinical efficacy of dendritic cells derived from bone marrow hematopoietic stem cells for the treatment of syngeneic prostate cancer immune cell therapy. Authors: Yunlim Kim, Choung-Soo Kim, and ...

Hematopoietic stem cells, which are derived from both blood and bone marrow, are known for their extraordinary regenerative properties -- they can differentiate into a whole series of specialised ...

This is ensured by hematopoietic stem cells, which are found in the bone marrow. The process of blood cell formation is very important for the maintenance of a functional immune system and ...

To be exact, they form from specific kinds of stem cells, called hematopoietic stem cells (HSCs). These, plus other kinds of stem cells, live in micro-environments within the bone marrow called ...