(A) ABC transporters: The normal functioning of ABCG8/ABCG5, ABCB4, and ABCB11 enables the transport of cholesterol, bile acids, and lipids into bile (left). Mutations in any of these result in ...

A large Danish study has shown that extreme levels of bilirubin in plasma are associated with an increased risk of developing symptomatic gallstone disease. The researchers used a Mendelian ...

You may develop jaundice if you have high bilirubin levels, a sign of liver damage. Gallstones can lead to a build-up of bilirubin in your blood. A doctor can use phototherapy to treat high bilirubin ...

The gallbladder is a small, grape sized, organ attached to the digestive tract. It secretes a fluid called bile into it in response to a meal. Bile emulsifies dietary fats by increasing their exposure ...

Gallstones are solid particles that form in the gallbladder, a small organ beneath the liver responsible for storing bile—a digestive fluid produced by the liver. These stones can vary in size, from ...

Gallstones are supersaturated, pebble-like deposits of bile inside the gallbladder. They can be as small as a grain of sand or as big as a golf ball and can occur as a single stone or as a collection ...

Cholelithiasis is the formation of gallstones due to bile imbalance, cholesterol supersaturation, or gallbladder hypomotility. It may cause biliary colic, nausea, and intolerance to fatty foods.

Americans’ bad diets are leading many people to have their gallbladders removed because of gallstones. The stones, which can vary in size, are not usually problematic if they are asymptomatic. People ...