The connection between perturbations in BBB barrier function and damage to the astrocyte network and its functions arises from BBB damage, leading to the extravasation of albumin. In the physiological ...

Increased expression of the Ang‐II (Angiotensin II) precursor AGT in aged astrocytes lead to increased Ang‐II signaling from aged astrocytes to endothelium, thus increasingblood–brain barrier (BBB) ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

Women are affected by severe depression twice as often as men. The reasons for this have not yet been fully clarified. One potential factor is sex-specific differences in the blood-brain barrier. This ...

The brain is among the most “immune-privileged” of organs primarily through the highly selective permeability of the blood-brain-barrier (BBB), its minimal lymphatic drainage, the presence of ...

Resting brain stem cells hardly differ from normal astrocytes, which support the nerve cells in the brain. How can almost identical cells perform such different functions? The key lies in the ...

A research team at the RIKEN Center for Biosystems Dynamics Research (BDR) in Japan report they have created a model of the blood-brain barrier using modularized tissue derived from human cells. The ...