Fenebrutinib significantly reduced new lesions with active inflammation in people with relapsing MS in a Phase 2 trial.

Researchers analyzed 12 MS lesion samples and seven control samples, focusing on chronic active (MS-CA) and chronic inactive (MS-CI) lesions based on markers like demyelination, inflammation, and ...

A second-generation anti-CD40L monoclonal antibody suppresses multiple sclerosis (MS) disease activity on MRI to an uncommonly high degree, new trial data suggested.

The study, the first to examine vaccine safety and immunogenicity in highly active MS, revealed high seroprotection rates following receipt of vaccines for COVID-19 and hepatitis A and B ...

More information: Allan Motyer et al, Neuronal somatic mutations are increased in multiple sclerosis lesions, Nature Neuroscience (2025). DOI: 10.1038/s41593-025-01895-5 ...

Researchers from Mātai Medical Research Institute in Gisborne are helping develop a new MRI scan method, which they say can detect subtle brain lesions in multiple sclerosis patients not seen on ...

Journal reference: Singhal, T., et al. (2022). Glial Activity Load on PET Reveals Persistent “Smoldering” Inflammation in MS Despite Disease-Modifying Treatment: 18: F-PBR06 Study.

Inflammation in MS Despite Disease-Modifying Treatment” Clinical Nuclear Medicine. DOI: 10.1097/RLU.0000000000005201 ...

Clinical Nuclear Medicine. doi.org/10.1097/RLU.0000000000005201. PET brain scans could reveal hidden inflammation in patients with multiple sclerosis© Provided by News Medical ...