Sesser is a city in Franklin County, Illinois, United States. The population was 1,888 at the 2020 census. The current mayor is C. Jason Ashmo…Sesser is a city in Franklin County, Illinois, United States. The population was 1,888 at the 2020 census. The current mayor is C. Jason Ashmore. In summer 1904, when coal was discovered at today's Sesser, the area was a prairie covered with wheat and corn fields. By 1906, the Chicago, Burlington and Quincy Railroad had extended its lines south from Centralia to Sesser, and the new town was named after railroad surveyor John Sesser.